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Low pathogenic infections salmon anemia virus (ISAv) in vivo: a comparative genomic study



Since the initial identification of ISAv in Norway in 1984, and in the Bay of Fundy in 1996, viral evolution and selective pressure, combined with improved detection have revealed an interesting and challenging Infectious Salmon Anaemia virus (ISAv) portrait: the presence of essentially avirulent strains such as the HPR0 variant, as well as highly virulent strains, such as HPR4 variants. Additionally there are many other strains identified which have varying degrees of virulence. The ISAv remains a looming threat to the salmon aquaculture industry, and ISAv continues to evolve. This study will contain an in-depth assessment of the etiology of ISAv to gain further understanding of the variable virulence and infection dynamics observed in vivo in salmon.

Program Name

Aquaculture Collaborative Research and Development Program (ACRDP)


2011 - 2015


Atlantic: Gulf of Maine, Scotian Shelf

Principal Investigator(s)

Nellie Gagné

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