Research Document 2021/018
Canadian Environmental Protection Act Indirect Human Health Assessment Report on the AquAdvantage® Salmon
By Ali, K. and Dugan, S.
Abstract
An indirect human health risk assessment was conducted on a genetically modified Atlantic Salmon (Salmo salar) known as the AquAdvantage® EO-1α Salmon (AAS) that was notified under the Canadian Environmental Protection Act (CEPA). This risk assessment examined the potential for the AAS to cause harmful effects to humans in Canada relative to wild-type Atlantic Salmon as a consequence of environmental exposure, including exposure in natural environments and environments under its intended use of manufacture and grow-out in a contained land-based facility in Prince Edward Island. Multiple redundant physical and biological containment measures are in place to prevent release and establishment in the Canadian environment. There is no evidence to suggest a risk of adverse human health effects at the exposure levels predicted for the general Canadian population from use of AAS for commercial grow-out in a contained land-based facility as well as other identified potential uses. As such, there is no expectation that AAS poses any more risks to human health than wild-type Atlantic Salmon.
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